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KMID : 0882419770200121125
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Korean Journal of Medicine
1977 Volume.20 No. 12 p.1125 ~ p.1129
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A Case of Gilbert`s Syndrome
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Roh Jae-Kyung
Lee Woo-Hyung
Chun Jai-Yoon
Kang Jin-Kyung
Park In-Suh
Choi Heung-Jai
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Abstract
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Gilbert´s Syndrome is the name most frequently used to describe a condition, which has been called idiopathic unconiugated hyperbilirubinemia, familial non-hemolytic jaundice or constitutional hepatic dysfunction. It is characterized by a benign, persistent, but variable elevation of the plasma unconjugated bilirubin.
A 27-year-old- dentist was admitted because of general malaise and intermittent jaundice. On physical examination, there were no specific findings except mild icteric sclera. Hematologic studies including Cooms´ test revealed normal. Liver function tests were within normal limits except slightly elevated serum total bilirubin. Histologic findings of the liver showed residual chronic nonspecific portal inflammation. Reduction in caloric intake to 400 a day for 72 hours resulted in a significant increase in the plasma bilirubin concentration(especially unconjugated form) in this patient.
Now he has no subjective symptoms and leads a normal activity without specific treatment, but mild hyperbilirubinemia with fluctuation (less than 3 mg%) persists.
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KEYWORD
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